

| カタログ番号 | HF883014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human SOX30 Polyclonal Antibody (HF883014) is a rabbit polyclonal antibody detecting SOX30 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SOX30 (Thr292-Gly403). | ||||||||
| ターゲット | Transcription factor SOX-30, SOX30 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O94993 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Transcription factor SOX-30 (SOX30) is a ~81 kDa protein. Acts both as a transcriptional activator and a repressor. Binds to the DNA sequence 5'-ACAAT-3' and shows a preference for guanine residues surrounding this core motif. Binds to its own promoter and activates its own transcription. Required to activate the expression of postmeiotic genes involved in spermiogenesis. Binds to the promoter region of CTNNB1 and represses its transcription which leads to inhibition of Wnt signaling. 1. Osaki, E. et al. (1999) Nucleic acids research 27, 2503-10. PMID: 10359848 2. Han, F. et al. (2018) EBioMedicine 31, 253-266. PMID: 29739711 | ||||||||
| 注意事項 | For research use only. |
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