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Anti-Human SPART Polyclonal Antibody (HC761014)

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Anti-Human SPART Polyclonal Antibody
Anti-Human SPART Polyclonal Antibody
Precio(USD): --
Especificación:
  • 50ug
  • 100ug
Número:
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Vista general
Número de catálogoHC761014
Descripción
Anti-Human SPART Polyclonal Antibody (HC761014) is a rabbit polyclonal antibody detecting SPART. Suitable for Mouse and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human SPART (Gly198-Gln336).
Objetivo KIAA0610, SPART, SPG20, Spartin, Spastic paraplegia 20 protein, TAHCCP1, Trans-activated by hepatitis C virus core protein 1
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q8N0X7
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Spartin is a ~72 kDa protein. Lipophagy receptor that plays an important role in lipid droplet (LD) turnover in motor neurons. Localizes to LDs and interacts with components of the autophagy machinery, such as MAP1LC3A/C proteins to deliver LDs to autophagosomes for degradation via lipophagy. Lipid transfer protein required for lipid droplet degradation, including by lipophagy. Can bind and transfer all lipid species found in lipid droplets, from phospholipids to triglycerides and sterol esters but the direction of lipid transfer by spartin and its cargos are unknown. May be implicated in endosomal trafficking, or microtubule dynamics, or both.

1. Chung, J. et al. (2023) Nature cell biology 25, 1101-1110. PMID: 37443287
2. Wan, N. et al. (2024) Proceedings of the National Academy of Sciences of the United States of America 121, e2314093121. PMID: 38190532
3. Renvoisé, B. et al. (2010) Molecular biology of the cell 21, 3293-303. PMID: 20719964
Nota For research use only
Imágenes
  • Anti-Human SPART Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-SPART polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Hela cell lysate
    Lane 2: PANC1 cell lysate
    Lane 3: HL-60 cell lysate
    Lane 4: MDA-MB-231 cell lysate
    Lane 5: K562 cell lysate
    Lane 6: 293T cell lysate
    Lane 7: Mouse heart lysate
    Lane 8: Rat heart lysate
    Lane 9: Mouse brain lysate
    Lane 10: Rat brain lysate
    Lane11: Mouse spleen lysate

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human SPART Polyclonal Antibody

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