中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HC761014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human SPART Polyclonal Antibody (HC761014) is a rabbit polyclonal antibody detecting SPART. Suitable for Mouse and Human.
Highlights
|
||||||||
| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SPART (Gly198-Gln336). | ||||||||
| ターゲット | KIAA0610, SPART, SPG20, Spartin, Spastic paraplegia 20 protein, TAHCCP1, Trans-activated by hepatitis C virus core protein 1 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8N0X7 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 背景 | Spartin is a ~72 kDa protein. Lipophagy receptor that plays an important role in lipid droplet (LD) turnover in motor neurons. Localizes to LDs and interacts with components of the autophagy machinery, such as MAP1LC3A/C proteins to deliver LDs to autophagosomes for degradation via lipophagy. Lipid transfer protein required for lipid droplet degradation, including by lipophagy. Can bind and transfer all lipid species found in lipid droplets, from phospholipids to triglycerides and sterol esters but the direction of lipid transfer by spartin and its cargos are unknown. May be implicated in endosomal trafficking, or microtubule dynamics, or both. 1. Chung, J. et al. (2023) Nature cell biology 25, 1101-1110. PMID: 37443287 2. Wan, N. et al. (2024) Proceedings of the National Academy of Sciences of the United States of America 121, e2314093121. PMID: 38190532 3. Renvoisé, B. et al. (2010) Molecular biology of the cell 21, 3293-303. PMID: 20719964 | ||||||||
| 注意事項 | For research use only |
Western blot analysis was performed using anti-SPART polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: PANC1 cell lysate
Lane 3: HL-60 cell lysate
Lane 4: MDA-MB-231 cell lysate
Lane 5: K562 cell lysate
Lane 6: 293T cell lysate
Lane 7: Mouse heart lysate
Lane 8: Rat heart lysate
Lane 9: Mouse brain lysate
Lane 10: Rat brain lysate
Lane11: Mouse spleen lysate
お問い合わせ
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
