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| カタログ番号 | HA888013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1862 | ||||
| ターゲット | Protein spinster homolog 2, SPNS2 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q8IVW8 | ||||
| RRID | Anti-Human SPNS2 Antibody (SAA1862) (abinScience Cat# HA888013, RRID:AB_3727625) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Sphingosine-1-phosphate transporter SPNS2 is a ~58 kDa protein. Lipid transporter that specifically mediates export of sphingosine-1-phosphate (sphing-4-enine 1-phosphate, S1P) and sphinganine-1-phosphate in the lymph, thereby playing a role in lymphocyte trafficking. S1P is a bioactive signaling molecule that regulates many physiological processes important for the development and for the immune system. Regulates levels of S1P and the S1P gradient that exists between the high circulating concentrations of S1P and low tissue levels that control lymphocyte trafficking. Required for the egress of T-cells from lymph nodes during an immune response by mediating S1P secretion, which generates a gradient that enables activated T-cells to access lymph. Also required for the egress of immature B-cells from the bone marrow. 1. Kawahara, A. et al. (2009) Science (New York, N.Y.) 323, 524-7. PMID: 19074308 2. Hisano, Y. et al. (2011) The Journal of biological chemistry 286, 1758-66. PMID: 21084291 3. Nagahashi, M. et al. (2013) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27, 1001-11. PMID: 23180825 4. Ingham, NJ. et al. (2019) PLoS biology 17, e3000194. PMID: 30973865 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human SPNS2 Antibody (SAA1862)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
