Anti-Human SPRR2A Polyclonal Antibody (HA621014)

Name: Anti-Human SPRR2A Polyclonal Antibody
Brand: abinScience
SKU: HA621014
Price: 168 USD
Availability: InStock

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Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HA621014

Описание

Anti-Human SPRR2A Polyclonal Antibody (HA621014) is a rabbit polyclonal antibody detecting Small proline-rich protein 2A; SPR-2A; 2-1; SPRR2A in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human SPRR2A (Ser2-Lys72).

Цель

Small proline-rich protein 2A; SPR-2A; 2-1; SPRR2A

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

P35326, P35325

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Small proline-rich protein 2A (SPRR2A) is a ~7 kDa protein. Gut bactericidal protein that selectively kills Gram-positive bacteria by binding to negatively charged lipids on bacterial membranes, leading to bacterial membrane permeabilization and disruption. Specifically binds lipids bearing negatively charged headgroups, such as phosphatidic acid, phosphatidylserine (PS), cardiolipin (CL), and phosphatidylinositol phosphates, but not to zwitterionic or neutral lipids. Induced by type-2 cytokines in response to helminth infection and is required to protect against helminth-induced bacterial invasion of intestinal tissue. May also be involved in the development of the cornified envelope of squamous epithelia; however, additional evidences are required to confirm this result in vivo.

1. Hu, Z. et al. (2021) Science (New York, N.Y.) 374, eabe6723. PMID: 34735226

2. Gibbs, S. et al. (1993) Genomics 16, 630-7. PMID: 8325635

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-Human SPRR2A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа