

| Numéro de catalogue | HY369014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human SRPRA Polyclonal Antibody (HY369014) is a rabbit polyclonal antibody detecting SRPRA in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human SRPRA (Arg335-Ala638). | ||||||||
| Cible | Signal recognition particle receptor subunit alpha, SR-alpha, Docking protein alpha, DP-alpha, SRPRA, SRPR | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P08240 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Signal recognition particle receptor subunit alpha (SRPRA) is a ~69 kDa protein. Component of the signal recognition particle (SRP) complex receptor (SR). Ensures, in conjunction with the SRP complex, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SRP subunit SRP54. SRP receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER. 1. Schlenker, O. et al. (2006) The Journal of biological chemistry 281, 8898-906. PMID: 16439358 2. Halic, M. et al. (2006) Science (New York, N.Y.) 312, 745-7. PMID: 16675701 3. Lee, JH. et al. (2021) Science advances 7. PMID: 34020957 | ||||||||
| Note | For research use only. |
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