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| カタログ番号 | HY369014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human SRPRA Polyclonal Antibody (HY369014) is a rabbit polyclonal antibody detecting SRPRA in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SRPRA (Arg335-Ala638). | ||||||||
| ターゲット | Signal recognition particle receptor subunit alpha, SR-alpha, Docking protein alpha, DP-alpha, SRPRA, SRPR | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P08240 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Signal recognition particle receptor subunit alpha (SRPRA) is a ~69 kDa protein. Component of the signal recognition particle (SRP) complex receptor (SR). Ensures, in conjunction with the SRP complex, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SRP subunit SRP54. SRP receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER. 1. Schlenker, O. et al. (2006) The Journal of biological chemistry 281, 8898-906. PMID: 16439358 2. Halic, M. et al. (2006) Science (New York, N.Y.) 312, 745-7. PMID: 16675701 3. Lee, JH. et al. (2021) Science advances 7. PMID: 34020957 | ||||||||
| 注意事項 | For research use only. |
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