中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HC271014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human SRY Polyclonal Antibody (HC271014) is a rabbit polyclonal antibody detecting SRY in ELISA, IHC, WB. Suitable for Human.
Highlights
|
||||||||
| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SRY (Met1-Leu204). | ||||||||
| ターゲット | TDF, Sex-determining region Y protein, Testis-determining factor, SRY | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q05066 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Sex-determining region Y protein (SRY) is a ~23 kDa protein. Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending. 1. Murphy, EC. et al. (2001) Journal of molecular biology 312, 481-99. PMID: 11563911 2. Oh, HJ. et al. (2006) Molecular and cellular endocrinology 247, 47-52. PMID: 16414182 3. Polanco, JC. et al. (2007) Developmental biology 302, 13-24. PMID: 16996051 4. Desclozeaux, M. et al. (1998) The Journal of biological chemistry 273, 7988-95. PMID: 9525897 5. Ferrari, S. et al. (1992) The EMBO journal 11, 4497-506. PMID: 1425584 6. Phillips, NB. et al. (2004) Biochemistry 43, 7066-81. PMID: 15170344 7. Giese, K. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 3368-72. PMID: 8159753 8. King, CY. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 11990-4. PMID: 8265659 | ||||||||
| 注意事項 | For research use only. |
お問い合わせ
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
