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Anti-Human STEAP3 Polyclonal Antibody (HP251014)

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Vista general
Número de catálogoHP251014
Descripción
Anti-Human STEAP3 Polyclonal Antibody (HP251014) is a rabbit polyclonal antibody detecting STEAP3 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human STEAP3 (Lys30-Arg207).
Objetivo hpHyde, STEAP3, pHyde, Tumor suppressor-activated pathway protein 6, TSAP6, Metalloreductase STEAP3, Six-transmembrane epithelial antigen of prostate 3, hTSAP6, Dudulin-2
Purificación Purified by antigen affinity column.
Número de acceso Q658P3
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Metalloreductase STEAP3 is a ~54 kDa protein. Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate. Can also reduce Cu(2+) to Cu(1+). Mediates efficient transferrin-dependent iron uptake in erythroid cells. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression.

1. Kleven, MD. et al. (2015) The Journal of biological chemistry 290, 22558-69. PMID: 26205815
2. Amzallag, N. et al. (2004) The Journal of biological chemistry 279, 46104-12. PMID: 15319436
3. Yu, X. et al. (2006) Cancer research 66, 4795-801. PMID: 16651434
Nota For research use only.
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Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human STEAP3 Polyclonal Antibody

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