

| Numéro de catalogue | HS851013 | ||||
|---|---|---|---|---|---|
| Reactivité des espèces | Human | ||||
| Applications | ELISA | ||||
| Espèce hôte | Mouse | ||||
| Clonalité | Monoclonal | ||||
| Isotype | IgG2a, kappa | ||||
| ID de clone | SAA1684 | ||||
| Cible | STX1A, STX1, Neuron-specific antigen HPC-1, Syntaxin-1A | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | Q16623 | ||||
| RRID | Anti-Human STX1A Antibody (SAA1684) (abinScience Cat# HS851013, RRID:AB_3727445) |
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| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Contexte | Syntaxin-1A (STX1A) is a ~33 kDa protein. Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis. Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane. STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles. The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final fusion. Participates in the calcium-dependent regulation of acrosomal exocytosis in sperm. 1. Craig, TJ. et al. (2015) Scientific reports 5, 17669. PMID: 26635000 2. Rodríguez, F. et al. (2012) The Journal of biological chemistry 287, 43825-39. PMID: 23091057 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human STX1A Antibody (SAA1684)
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