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| カタログ番号 | HT319014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human SULT1B1 Polyclonal Antibody (HT319014) is a rabbit polyclonal antibody detecting SULT1B1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human SULT1B1 (Met1-Ile296). | ||||||||
| ターゲット | Sulfotransferase 1B1, ST1B1, 2.8.2.1, Sulfotransferase 1B2, Sulfotransferase family cytosolic 1B member 1, Thyroid hormone sulfotransferase, SULT1B1, ST1B2, SULT1B2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O43704 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Sulfotransferase 1B1 (SULT1B1) is a ~34 kDa protein. Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine (T3) and reverse triiodothyronine (rT3). May play a role in gut microbiota-host metabolic interaction. O-sulfonates 4-ethylphenol (4-EP), a dietary tyrosine-derived metabolite produced by gut bacteria. The product 4-EPS crosses the blood-brain barrier and may negatively regulate oligodendrocyte maturation and myelination, affecting the functional connectivity of different brain regions associated with the limbic system. 1. Tibbs, ZE. et al. (2018) Xenobiotica; the fate of foreign compounds in biological systems 48, 79-88. PMID: 28084139 2. Fujita, K. et al. (1997) Journal of biochemistry 122, 1052-61. PMID: 9443824 3. Wang, J. et al. (1998) Molecular pharmacology 53, 274-82. PMID: 9463486 4. Needham, BD. et al. (2022) Nature 602, 647-653. PMID: 35165440 | ||||||||
| 注意事項 | For research use only. |
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