

| Número de catálogo | HT423014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human SULT1C2 (Lys12-Leu296). | ||||||||
| Objetivo | SULT1C2, humSULTC2, Sulfotransferase 1C1, ST1C2, SULT1C#1, SULT1C1, Sulfotransferase 1C2 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O00338 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Sulfotransferase 1C2 (SULT1C2) is a ~34 kDa protein. Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the sulfate conjugation of phenolic compounds. Does not transfer sulfate to steroids, dopamine, acetaminophen, or alpha-naphthol. Except in mitochondria, where it can add sulfate to cholesterol producing cholesterol sulfate, which alters mitochondrial membrane organization, and impacts protein complex mobility increasing state-III respiration, thereby modulating mitochondrial respiration. Catalyzes the sulfation of the carcinogenic N-hydroxy-2-acetylaminofluorene leading to highly reactive intermediates capable of forming DNA adducts, potentially resulting in mutagenesis. 1. Hehonah, N. et al. (1999) The international journal of biochemistry & cell biology 31, 869-82. PMID: 10481272 2. Freimuth, RR. et al. (2000) Genomics 65, 157-65. PMID: 10783263 3. Sakakibara, Y. et al. (1998) The Journal of biological chemistry 273, 33929-35. PMID: 9852044 | ||||||||
| Nota | For research use only. |
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