Anti-Human SULT2A1 Polyclonal Antibody (HB426014)

Name: Anti-Human SULT2A1 Polyclonal Antibody
Brand: abinScience
SKU: HB426014
Price: 96 USD
Availability: InStock

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Número de catálogo

HB426014

Descripción

Anti-Human SULT2A1 Polyclonal Antibody (HB426014) is a rabbit polyclonal antibody detecting Sulfotransferase 2A1; ST2A1; 2.8.2.2; Bile salt sulfotransferase; 2.8.2.14; Dehydroepiandrosterone sulfotransferase; DHEA-ST; DHEA-ST8; Hydroxysteroid Sulfotransferase; HST; ST2; SULT2A3; SULT2A1; HST; STD in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant human SULT2A1 (Met1-Glu285).

Objetivo

Sulfotransferase 2A1; ST2A1; 2.8.2.2; Bile salt sulfotransferase; 2.8.2.14; Dehydroepiandrosterone sulfotransferase; DHEA-ST; DHEA-ST8; Hydroxysteroid Sulfotransferase; HST; ST2; SULT2A3; SULT2A1; HST; STD

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

Q06520

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Sulfotransferase 2A1 (SULT2A1) is a ~33 kDa protein. Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. Mediates the sulfation of a wide range of steroids and sterols, including pregnenolone, androsterone, DHEA, bile acids, cholesterol and as well many xenobiotics that contain alcohol and phenol functional groups. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Plays an important role in maintening steroid and lipid homeostasis. Plays a key role in bile acid metabolism, mediating formation of 3-sulfated bile acids.

1. Chang, HJ. et al. (2004) The Journal of biological chemistry 279, 2689-96. PMID: 14573603

2. Lu, LY. et al. (2008) Molecular pharmacology 73, 660-8. PMID: 18042734

3. Cook, IT. et al. (2009) Drug metabolism and disposition: the biological fate of chemicals 37, 2069-78. PMID: 19589875

4. Huang, J. et al. (2010) Xenobiotica; the fate of foreign compounds in biological systems 40, 184-94. PMID: 20102295

5. Gulcan, HO. et al. (2011) Archives of biochemistry and biophysics 507, 232-40. PMID: 21187059

6. Radominska, A. et al. (1990) The Biochemical journal 272, 597-604. PMID: 2268288

7. Abunnaja, MS. et al. (2018) Biochemistry and cell biology = Biochimie et biologie cellulaire 96, 655-662. PMID: 29671343

8. Comer, KA. et al. (1993) The Biochemical journal 289 ( Pt 1), 233-40. PMID: 7678732

9. Glatt, H. et al. (1994) Mutagenesis 9, 553-7. PMID: 7854148

Nota

For research use only

Imágenes

Western blot

Western blot analysis was performed using anti-SULT2A1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate

Referencias

Datasheet

Anti-Human SULT2A1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human SULT2A1 Polyclonal Antibody (HB426014)

Vista general

Imágenes

Referencias

Datasheet

SDS