Anti-Human SULT2A1 Polyclonal Antibody (HB426014)

Name: Anti-Human SULT2A1 Polyclonal Antibody
Brand: abinScience
SKU: HB426014
Price: 96 USD
Availability: InStock

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SDS

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Каталожный номер

HB426014

Описание

Anti-Human SULT2A1 Polyclonal Antibody (HB426014) is a rabbit polyclonal antibody detecting Sulfotransferase 2A1; ST2A1; 2.8.2.2; Bile salt sulfotransferase; 2.8.2.14; Dehydroepiandrosterone sulfotransferase; DHEA-ST; DHEA-ST8; Hydroxysteroid Sulfotransferase; HST; ST2; SULT2A3; SULT2A1; HST; STD in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human SULT2A1 (Met1-Glu285).

Цель

Sulfotransferase 2A1; ST2A1; 2.8.2.2; Bile salt sulfotransferase; 2.8.2.14; Dehydroepiandrosterone sulfotransferase; DHEA-ST; DHEA-ST8; Hydroxysteroid Sulfotransferase; HST; ST2; SULT2A3; SULT2A1; HST; STD

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

Q06520

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Sulfotransferase 2A1 (SULT2A1) is a ~33 kDa protein. Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. Mediates the sulfation of a wide range of steroids and sterols, including pregnenolone, androsterone, DHEA, bile acids, cholesterol and as well many xenobiotics that contain alcohol and phenol functional groups. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Plays an important role in maintening steroid and lipid homeostasis. Plays a key role in bile acid metabolism, mediating formation of 3-sulfated bile acids.

1. Chang, HJ. et al. (2004) The Journal of biological chemistry 279, 2689-96. PMID: 14573603

2. Lu, LY. et al. (2008) Molecular pharmacology 73, 660-8. PMID: 18042734

3. Cook, IT. et al. (2009) Drug metabolism and disposition: the biological fate of chemicals 37, 2069-78. PMID: 19589875

4. Huang, J. et al. (2010) Xenobiotica; the fate of foreign compounds in biological systems 40, 184-94. PMID: 20102295

5. Gulcan, HO. et al. (2011) Archives of biochemistry and biophysics 507, 232-40. PMID: 21187059

6. Radominska, A. et al. (1990) The Biochemical journal 272, 597-604. PMID: 2268288

7. Abunnaja, MS. et al. (2018) Biochemistry and cell biology = Biochimie et biologie cellulaire 96, 655-662. PMID: 29671343

8. Comer, KA. et al. (1993) The Biochemical journal 289 ( Pt 1), 233-40. PMID: 7678732

9. Glatt, H. et al. (1994) Mutagenesis 9, 553-7. PMID: 7854148

Примечание

For research use only

Изображения

Western blot

Western blot analysis was performed using anti-SULT2A1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate

Ссылки

Даташит

Anti-Human SULT2A1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human SULT2A1 Polyclonal Antibody (HB426014)

Обзор

Изображения

Ссылки

Даташит

SDS