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Anti-Human SULT2B1 Polyclonal Antibody (HT231014)

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Vista general
Número de catálogoHT231014
Descripción
Anti-Human SULT2B1 Polyclonal Antibody (HT231014) is a rabbit polyclonal antibody detecting SULT2B1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human SULT2B1 (Gly29-Gly303).
Objetivo Sulfotransferase 2B1, 2.8.2.2, Alcohol sulfotransferase, Hydroxysteroid sulfotransferase 2, Sulfotransferase family 2B member 1, Sulfotransferase family cytosolic 2B member 1, ST2B1, SULT2B1, HSST2
Purificación Purified by antigen affinity column.
Número de acceso O00204
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Sulfotransferase 2B1 (SULT2B1) is a ~41 kDa protein. Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Responsible for the sulfation of cholesterol. Catalyzes sulfation of the 3beta-hydroxyl groups of steroids, such as, pregnenolone and dehydroepiandrosterone (DHEA). Preferentially sulfonates cholesterol, while it also has significant activity with pregnenolone and DHEA. Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation.

1. Fuda, H. et al. (2002) The Journal of biological chemistry 277, 36161-6. PMID: 12145317
2. Cook, IT. et al. (2009) Drug metabolism and disposition: the biological fate of chemicals 37, 2069-78. PMID: 19589875
3. He, D. et al. (2006) Drug metabolism and disposition: the biological fate of chemicals 34, 1749-55. PMID: 16855051
4. Salman, ED. et al. (2011) The Journal of steroid biochemistry and molecular biology 127, 315-23. PMID: 21855633
5. Her, C. et al. (1998) Genomics 53, 284-95. PMID: 9799594
6. Heinz, L. et al. (2017) American journal of human genetics 100, 926-939. PMID: 28575648
Nota For research use only.
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Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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