

| Каталожный номер | HT231014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human SULT2B1 Polyclonal Antibody (HT231014) is a rabbit polyclonal antibody detecting SULT2B1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human SULT2B1 (Gly29-Gly303). | ||||||||
| Цель | Sulfotransferase 2B1, 2.8.2.2, Alcohol sulfotransferase, Hydroxysteroid sulfotransferase 2, Sulfotransferase family 2B member 1, Sulfotransferase family cytosolic 2B member 1, ST2B1, SULT2B1, HSST2 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | O00204 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Sulfotransferase 2B1 (SULT2B1) is a ~41 kDa protein. Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Responsible for the sulfation of cholesterol. Catalyzes sulfation of the 3beta-hydroxyl groups of steroids, such as, pregnenolone and dehydroepiandrosterone (DHEA). Preferentially sulfonates cholesterol, while it also has significant activity with pregnenolone and DHEA. Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation. 1. Fuda, H. et al. (2002) The Journal of biological chemistry 277, 36161-6. PMID: 12145317 2. Cook, IT. et al. (2009) Drug metabolism and disposition: the biological fate of chemicals 37, 2069-78. PMID: 19589875 3. He, D. et al. (2006) Drug metabolism and disposition: the biological fate of chemicals 34, 1749-55. PMID: 16855051 4. Salman, ED. et al. (2011) The Journal of steroid biochemistry and molecular biology 127, 315-23. PMID: 21855633 5. Her, C. et al. (1998) Genomics 53, 284-95. PMID: 9799594 6. Heinz, L. et al. (2017) American journal of human genetics 100, 926-939. PMID: 28575648 | ||||||||
| Примечание | For research use only. |
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