Anti-Human SUZ12 Polyclonal Antibody (HC259014)

Name: Anti-Human SUZ12 Polyclonal Antibody
Brand: abinScience
SKU: HC259014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HC259014

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human SUZ12 (Lys587-Gly691).

Objetivo

SUZ12, Polycomb protein SUZ12, Joined to JAZF1 protein, CHET9, KIAA0160, ChET 9 protein, Suppressor of zeste 12 protein homolog, Chromatin precipitated E2F target 9 protein, JJAZ1

Purificación

Purified by antigen affinity column.

Número de acceso

Q15022

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Polycomb protein SUZ12 is a ~83 kDa protein. Polycomb group (PcG) protein. Component of the PRC2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

1. Cao, R. et al. (2004) Molecular cell 15, 57-67. PMID: 15225548

2. Kirmizis, A. et al. (2004) Genes & development 18, 1592-605. PMID: 15231737

3. Pasini, D. et al. (2004) The EMBO journal 23, 4061-71. PMID: 15385962

4. Bracken, AP. et al. (2006) Genes & development 20, 1123-36. PMID: 16618801

5. Bracken, AP. et al. (2007) Genes & development 21, 525-30. PMID: 17344414

6. Sarma, K. et al. (2008) Molecular and cellular biology 28, 2718-31. PMID: 18285464

7. Imagawa, E. et al. (2017) Human mutation 38, 637-648. PMID: 28229514

8. Chen, S. et al. (2018) Molecular cell 69, 840-852.e5. PMID: 29499137

9. Chen, S. et al. (2020) Molecular cell 77, 1265-1278.e7. PMID: 31959557

10. Cao, R. et al. (2002) Science (New York, N.Y.) 298, 1039-43. PMID: 12351676

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human SUZ12 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo