

| Numéro de catalogue | HF800014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human SVIL Polyclonal Antibody (HF800014) is a rabbit polyclonal antibody detecting SVIL. Suitable for Mouse and Human.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human SVIL (Met1444-Lys1678). | ||||||||
| Cible | Archvillin, SVIL, Supervillin, p205/p250 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O95425 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Supervillin (SVIL) is a ~247 kDa protein. Forms a high-affinity link between the actin cytoskeleton and the membrane. Is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. 1. Oh, SW. et al. (2003) Journal of cell science 116, 2261-75. PMID: 12711699 2. Crowley, JL. et al. (2009) Molecular biology of the cell 20, 948-62. PMID: 19109420 3. Laurent, B. et al. (2015) Molecular cell 57, 957-970. PMID: 25684206 | ||||||||
| Note | For research use only |
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