

| Каталожный номер | HT190014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human SYT7 Polyclonal Antibody (HT190014) is a rabbit polyclonal antibody detecting SYT7 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
||||||||
| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human SYT7 (Gly137-Ala403). | ||||||||
| Цель | Synaptotagmin-7, IPCA-7, Prostate cancer-associated protein 7, Synaptotagmin VII, SytVII, SYT7, PCANAP7 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | O43581 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
||||||||
| Информация об использовании продукта |
| ||||||||
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Synaptotagmin-7 (SYT7) is a ~45 kDa protein. Ca(2+) sensor involved in Ca(2+)-dependent exocytosis of secretory and synaptic vesicles through Ca(2+) and phospholipid binding to the C2 domain. Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis. SYT7 binds Ca(2+) with high affinity and slow kinetics compared to other synaptotagmins. Involved in Ca(2+)-triggered lysosomal exocytosis, a major component of the plasma membrane repair. Ca(2+)-regulated delivery of lysosomal membranes to the cell surface is also involved in the phagocytic uptake of particles by macrophages. 1. Caler, EV. et al. (2001) The Journal of experimental medicine 193, 1097-104. PMID: 11342594 2. Chakrabarti, S. et al. (2005) Molecular and biochemical parasitology 141, 125-8. PMID: 15811535 | ||||||||
| Примечание | For research use only. |
Свяжитесь с нами для индивидуальных предложений, оптовых запросов и других вопросов.
Почта: [email protected]
+86-027-65523339
Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский