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Anti-Human TACR3 Polyclonal Antibody (HB075014)

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Vista general
Número de catálogoHB075014
Descripción
Anti-Human TACR3 Polyclonal Antibody (HB075014) is a rabbit polyclonal antibody detecting TACR3 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human TACR3 (Ala2-Arg84).
Objetivo Neuromedin-K receptor, NKR, NK-3 receptor, NK-3R, Neurokinin B receptor, Tachykinin receptor 3, TACR3, NK3R, TAC3R
Purificación Purified by antigen affinity column.
Número de acceso P29371
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Neuromedin-K receptor (TACR3) is a ~52 kDa protein. Receptor for the tachykinin neuromedin-K (neurokinin B), also able to bind and respond to tachynins substance K/neurokinin A and substance P. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K and substance P. Neuromedin-K binding to its receptor triggers G protein-coupled receptor signaling via activation of G(q) and phosphatidylinositol hydrolysis by phospholipase C. Neuromedin-K binding also triggers signaling via activation of adenylate cyclase activity which results in increased intracellular levels of cyclic AMP (cAMP).

1. Buell, G. et al. (1992) FEBS letters 299, 90-5. PMID: 1312036
2. Sun, W. et al. (2023) Cell discovery 9, 66. PMID: 37391393
Nota For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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