Anti-Human TAF1 Polyclonal Antibody (HB919014)

Name: Anti-Human TAF1 Polyclonal Antibody
Brand: abinScience
SKU: HB919014
Price: 96 USD
Availability: InStock

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Especificación:

20ug
50ug
100ug

Número:

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Datasheet
SDS

Vista general

Número de catálogo

HB919014

Descripción

Anti-Human TAF1 Polyclonal Antibody (HB919014) is a rabbit polyclonal antibody detecting TAF1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human TAF1 (Ser635-Gly944).

Objetivo

p250, TAF(II)250, CCGS, BA2R, TAF1, Transcription initiation factor TFIID subunit 1, Cell cycle gene 1 protein, TAFII-250, TAF2A, CCG1, TBP-associated factor 250 kDa, Transcription initiation factor TFIID 250 kDa subunit, TAFII250

Purificación

Purified by antigen affinity column.

Número de acceso

P21675

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Transcription initiation factor TFIID subunit 1 (TAF1) is a ~214 kDa protein. The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. TAF1 is the largest component and core scaffold of the TFIID complex, involved in nucleating complex assembly. TAF1 forms a promoter DNA binding subcomplex of TFIID, together with TAF7 and TAF2.

1. Chen, X. et al. (2021) Science (New York, N.Y.) 372. PMID: 33795473

2. Wang, H. et al. (2014) Cell research 24, 1433-44. PMID: 25412659

3. Louder, RK. et al. (2016) Nature 531, 604-9. PMID: 27007846

4. Dikstein, R. et al. (1996) Cell 84, 781-90. PMID: 8625415

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-TAF1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: 293T cell lysate
Lane 2: Jurkat cell lysate