Anti-Human TAF1 Polyclonal Antibody (HB919014)

Name: Anti-Human TAF1 Polyclonal Antibody
Brand: abinScience
SKU: HB919014
Price: 96 USD
Availability: InStock

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Aperçu
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Fiche technique
SDS

Aperçu

Numéro de catalogue

HB919014

Description

Anti-Human TAF1 Polyclonal Antibody (HB919014) is a rabbit polyclonal antibody detecting TAF1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human TAF1 (Ser635-Gly944).

Cible

p250, TAF(II)250, CCGS, BA2R, TAF1, Transcription initiation factor TFIID subunit 1, Cell cycle gene 1 protein, TAFII-250, TAF2A, CCG1, TBP-associated factor 250 kDa, Transcription initiation factor TFIID 250 kDa subunit, TAFII250

Purification

Purified by antigen affinity column.

Numéro d'accès

P21675

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Transcription initiation factor TFIID subunit 1 (TAF1) is a ~214 kDa protein. The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. TAF1 is the largest component and core scaffold of the TFIID complex, involved in nucleating complex assembly. TAF1 forms a promoter DNA binding subcomplex of TFIID, together with TAF7 and TAF2.

1. Chen, X. et al. (2021) Science (New York, N.Y.) 372. PMID: 33795473

2. Wang, H. et al. (2014) Cell research 24, 1433-44. PMID: 25412659

3. Louder, RK. et al. (2016) Nature 531, 604-9. PMID: 27007846

4. Dikstein, R. et al. (1996) Cell 84, 781-90. PMID: 8625415

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-TAF1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: 293T cell lysate
Lane 2: Jurkat cell lysate