

| Número de catálogo | HP986013 | ||||||
|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human | ||||||
| Aplicaciones | ELISA, WB | ||||||
| Especie huésped | Mouse | ||||||
| Clonalidad | Monoclonal | ||||||
| Isotipo | IgG2a | ||||||
| ID de clon | SAA1465 | ||||||
| Objetivo | Chemokine-like protein TAFA-5, TAFA5, FAM19A5 | ||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||
| Pureza | >95% as determined by SDS-PAGE. | ||||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||||
| Número de acceso | Q7Z5A7 | ||||||
| RRID | Anti-Human TAFA5/FAM19A5 Antibody (SAA1465) (abinScience Cat# HP986013, RRID:AB_3727121) |
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| Forma | Liquid | ||||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| Fondo | Chemokine-like protein TAFA-5 (TAFA5/FAM19A5) is a ~14 kDa protein. Acts as a chemokine-like protein by regulating cell proliferation and migration through activation of G protein-coupled receptors (GPCRs), such as S1PR2 and FPR2. Stimulates chemotactic migration of macrophages mediated by the MAPK3/ERK1 and AKT1 pathway. Blocks TNFSF11/RANKL-induced osteoclast formation from macrophages by inhibiting up-regulation of osteoclast fusogenic and differentiation genes. Stimulation of macrophage migration and inhibition of osteoclast formation is mediated via GPCR FPR2. Acts as an adipokine by negatively regulating vascular smooth muscle cell (VSMC) proliferation and migration in response to platelet-derived growth factor stimulation via GPCR S1PR2 and G protein GNA12/GNA13-transmitted RHOA signaling. | ||||||
| Nota | For research use only. |

SDS-PAGE for Anti-Human TAFA5/FAM19A5 Antibody (SAA1465)
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