

| Numéro de catalogue | HP986013 | ||||||
|---|---|---|---|---|---|---|---|
| Reactivité des espèces | Human | ||||||
| Applications | ELISA, WB | ||||||
| Espèce hôte | Mouse | ||||||
| Clonalité | Monoclonal | ||||||
| Isotype | IgG2a | ||||||
| ID de clone | SAA1465 | ||||||
| Cible | Chemokine-like protein TAFA-5, TAFA5, FAM19A5 | ||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||
| Pureté | >95% as determined by SDS-PAGE. | ||||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||||
| Numéro d'accès | Q7Z5A7 | ||||||
| RRID | Anti-Human TAFA5/FAM19A5 Antibody (SAA1465) (abinScience Cat# HP986013, RRID:AB_3727121) |
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| Forme | Liquid | ||||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| Contexte | Chemokine-like protein TAFA-5 (TAFA5/FAM19A5) is a ~14 kDa protein. Acts as a chemokine-like protein by regulating cell proliferation and migration through activation of G protein-coupled receptors (GPCRs), such as S1PR2 and FPR2. Stimulates chemotactic migration of macrophages mediated by the MAPK3/ERK1 and AKT1 pathway. Blocks TNFSF11/RANKL-induced osteoclast formation from macrophages by inhibiting up-regulation of osteoclast fusogenic and differentiation genes. Stimulation of macrophage migration and inhibition of osteoclast formation is mediated via GPCR FPR2. Acts as an adipokine by negatively regulating vascular smooth muscle cell (VSMC) proliferation and migration in response to platelet-derived growth factor stimulation via GPCR S1PR2 and G protein GNA12/GNA13-transmitted RHOA signaling. | ||||||
| Note | For research use only. |

SDS-PAGE for Anti-Human TAFA5/FAM19A5 Antibody (SAA1465)
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