

| Каталожный номер | HP986013 | ||||||
|---|---|---|---|---|---|---|---|
| Реактивность видов | Human | ||||||
| Применения | ELISA, WB | ||||||
| Хозяинский вид | Mouse | ||||||
| Клоональность | Monoclonal | ||||||
| Изотип | IgG2a | ||||||
| ID клона | SAA1465 | ||||||
| Цель | Chemokine-like protein TAFA-5, TAFA5, FAM19A5 | ||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||
| Чистота | >95% as determined by SDS-PAGE. | ||||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||||
| Номер доступа | Q7Z5A7 | ||||||
| RRID | Anti-Human TAFA5/FAM19A5 Antibody (SAA1465) (abinScience Cat# HP986013, RRID:AB_3727121) |
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| Форма | Liquid | ||||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| Фон | Chemokine-like protein TAFA-5 (TAFA5/FAM19A5) is a ~14 kDa protein. Acts as a chemokine-like protein by regulating cell proliferation and migration through activation of G protein-coupled receptors (GPCRs), such as S1PR2 and FPR2. Stimulates chemotactic migration of macrophages mediated by the MAPK3/ERK1 and AKT1 pathway. Blocks TNFSF11/RANKL-induced osteoclast formation from macrophages by inhibiting up-regulation of osteoclast fusogenic and differentiation genes. Stimulation of macrophage migration and inhibition of osteoclast formation is mediated via GPCR FPR2. Acts as an adipokine by negatively regulating vascular smooth muscle cell (VSMC) proliferation and migration in response to platelet-derived growth factor stimulation via GPCR S1PR2 and G protein GNA12/GNA13-transmitted RHOA signaling. | ||||||
| Примечание | For research use only. |

SDS-PAGE for Anti-Human TAFA5/FAM19A5 Antibody (SAA1465)
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