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| カタログ番号 | HP216014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human TBC1D23 (Gly15-Lys306). | ||||||||
| ターゲット | NS4ATP1, TBC1D23, TBC1 domain family member 23, HCV non-structural protein 4A-transactivated protein 1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9NUY8 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | TBC1 domain family member 23 (TBC1D23) is a ~78 kDa protein. Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. Plays a role in brain development, including in cortical neuron positioning. 1. Ivanova, EL. et al. (2017) American journal of human genetics 101, 428-440. PMID: 28823707 2. Shin, JJH. et al. (2017) Nature cell biology 19, 1424-1432. PMID: 29084197 3. Navarro Negredo, P. et al. (2018) Nature communications 9, 596. PMID: 29426865 | ||||||||
| 注意事項 | For research use only. |
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