

| Número de catálogo | HS883014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human TBR1 Polyclonal Antibody (HS883014) is a rabbit polyclonal antibody detecting TBR1 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human TBR1 (Lys203-Asn394). | ||||||||
| Objetivo | TES-56, TBR-1, T-box brain protein 1, T-brain-1, TBR1 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q16650 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | T-box brain protein 1 (TBR1) is a ~74 kDa protein. Transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection. As transcriptional repressor of FEZF2, it blocks the formation of the corticospinal (CS) tract from layer 6 projection neurons, thereby restricting the origin of CS axons specifically to layer 5 neurons. 1. Deriziotis, P. et al. (2014) Nature communications 5, 4954. PMID: 25232744 2. den Hoed, J. et al. (2018) Scientific reports 8, 14279. PMID: 30250039 | ||||||||
| Nota | For research use only. |
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