

| Numéro de catalogue | HS883014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human TBR1 Polyclonal Antibody (HS883014) is a rabbit polyclonal antibody detecting TBR1 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human TBR1 (Lys203-Asn394). | ||||||||
| Cible | TES-56, TBR-1, T-box brain protein 1, T-brain-1, TBR1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q16650 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | T-box brain protein 1 (TBR1) is a ~74 kDa protein. Transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection. As transcriptional repressor of FEZF2, it blocks the formation of the corticospinal (CS) tract from layer 6 projection neurons, thereby restricting the origin of CS axons specifically to layer 5 neurons. 1. Deriziotis, P. et al. (2014) Nature communications 5, 4954. PMID: 25232744 2. den Hoed, J. et al. (2018) Scientific reports 8, 14279. PMID: 30250039 | ||||||||
| Note | For research use only. |
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