

| Número de catálogo | HP788014 | ||||||||
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| Descripción |
Anti-Human TCF7L1 Polyclonal Antibody (HP788014) is a rabbit polyclonal antibody detecting TCF7L1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human TCF7L1 (Asn351-Gly445). | ||||||||
| Objetivo | TCF7L1, TCF3, HMG box transcription factor 3, TCF-3, Transcription factor 7-like 1 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9HCS4 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Transcription factor 7-like 1 (TCF7L1) is a ~62 kDa protein. Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. Down-regulates NQO1, leading to increased mitomycin c resistance. | ||||||||
| Nota | For research use only. |
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