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Anti-Human TCIRG1 Polyclonal Antibody (HC655014)

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Vista general
Número de catálogoHC655014
Descripción
Anti-Human TCIRG1 Polyclonal Antibody (HC655014) is a rabbit polyclonal antibody detecting TCIRG1/TIRC7 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human TCIRG1 (Met1-Glu385).
Objetivo TCIRG1, Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3, V-ATPase 116 kDa subunit a3, V-type proton ATPase 116 kDa subunit a3, ATP6V0A3, ATP6N1C, Osteoclastic proton pump 116 kDa subunit, TIRC7, T-cell immune response cDNA7 protein, T-cell immune regulator 1, OC-116 kDa, OC116
Purificación Purified by antigen affinity column.
Número de acceso Q13488
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

V-type proton ATPase 116 kDa subunit a 3 (TCIRG1/TIRC7) is a ~92 kDa protein. Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Seems to be directly involved in T-cell activation.

1. Heinemann, T. et al. (1999) Genomics 57, 398-406. PMID: 10329006
Nota For research use only.
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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