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| カタログ番号 | HP228013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA, IF, IP | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG | ||||
| クローンID | SAA0234 | ||||
| ターゲット | TDRD3, Tudor domain-containing protein 3 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q9H7E2 | ||||
| RRID | Anti-Human TDRD3 IP Antibody (SAA0234) (abinScience Cat# HP228013, RRID:AB_3729768) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Tudor domain-containing protein 3 (TDRD3) is a ~73 kDa protein. Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1. 1. Côté, J. et al. (2005) The Journal of biological chemistry 280, 28476-83. PMID: 15955813 2. Yang, Y. et al. (2010) Molecular cell 40, 1016-23. PMID: 21172665 3. Deater, M. et al. (2022) PLoS pathogens 18, e1010249. PMID: 35085371 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human TDRD3 IP Antibody (SAA0234)
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