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| カタログ番号 | HF743015 |
|---|---|
| 説明 |
Anti-Human TG/Thyroglobulin Monoclonal Antibody (1A305) [1A305] (HF743015) is a mouse monoclonal antibody detecting Thyroglobulin in ELISA. Suitable for Human.
|
| 種反応性 | Human |
| アプリケーション | ELISA |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG |
| クローンID | 1A305 |
| 免疫原 | Human TG/Thyroglobulin Protein. |
| ターゲット | Thyroglobulin, Tg, TG |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P01266 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Thyroglobulin (TG) is a ~304 kDa protein. Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules. 1. Caputo, M. et al. (2007) Clinical endocrinology 67, 351-7. PMID: 17532758 2. Coscia, F. et al. (2020) Nature 578, 627-630. PMID: 32025030 |
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human TG/Thyroglobulin Monoclonal Antibody (1A305)
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