Anti-Human TIF1/TRIM24 IP Recombinant Antibody (SAA0265) (HT332013)

Name: Anti-Human TIF1/TRIM24 IP Recombinant Antibody (SAA0265)
Brand: abinScience
SKU: HT332013
Price: 191 USD
Availability: InStock

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Спецификация:

50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HT332013

Реактивность видов

Human

Применения

ELISA, IF, IP

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a

ID клона

SAA0265

Цель

RING-type E3 ubiquitin transferase TIF1-alpha, TIF1-alpha, RING finger protein 82, Transcription intermediary factor 1-alpha, RNF82, Tripartite motif-containing protein 24, E3 ubiquitin-protein ligase TRIM24, TIF1, TIF1A, TRIM24

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

O15164

RRID

Anti-Human TIF1/TRIM24 IP Antibody (SAA0265) (abinScience Cat# HT332013, RRID:AB_3729799)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Transcription intermediary factor 1-alpha (TIF1/TRIM24) is a ~116 kDa protein. Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. During the DNA damage response, participates in an autoregulatory feedback loop with TP53. Early in response to DNA damage, ATM kinase phosphorylates TRIM24 leading to its ubiquitination and degradation.

1. Jain, AK. et al. (2014) Molecular and cellular biology 34, 2695-709. PMID: 24820418

2. Zhu, Q. et al. (2020) The Journal of experimental medicine 217. PMID: 32324863

3. Hang, Y. et al. (2021) Cell biology international 45, 1561-1570. PMID: 33724611

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human TIF1/TRIM24 IP Antibody (SAA0265)

Ссылки

Даташит

Anti-Human TIF1/TRIM24 IP Recombinant Antibody (SAA0265).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

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