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Anti-Human TM4SF20 Recombinant Antibody (SAA1694) (HS891013)

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Anti-Human TM4SF20 Recombinant Antibody (SAA1694)
Anti-Human TM4SF20 Recombinant Antibody (SAA1694)
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Vista general
Número de catálogoHS891013
Descripción
Anti-Human TM4SF20 Recombinant Antibody (SAA1694) (HS891013) is a mouse monoclonal antibody detecting TM4SF20 in ELISA. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
Reactividad de especiesHuman
AplicacionesELISA
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonSAA1694
Objetivo Transmembrane 4 L6 family member 20, TM4SF20
Nivel de endotoxinas < 10 EU/mg as determined by LAL method.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso Q53R12
RRID Anti-Human TM4SF20 Antibody (SAA1694) (abinScience Cat# HS891013, RRID:AB_3727455)
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Transmembrane 4 L6 family member 20 (TM4SF20) is a ~25 kDa protein. Polytopic transmembrane protein that inhibits regulated intramembrane proteolysis (RIP) of CREB3L1, inhibiting its activation and the induction of collagen synthesis. In response to ceramide, which alters TM4SF20 membrane topology, stimulates RIP activation of CREB3L1. Ceramide reverses the direction through which transmembrane helices are translocated into the endoplasmic reticulum membrane during translation of TM4SF20, this mechanism is called 'regulated alternative translocation' (RAT) and regulates the function of the transmembrane protein.

1. Chen, Q. et al. (2014) PloS one 9, e108528. PMID: 25310401
2. Chen, Q. et al. (2016) Molecular cell 63, 567-578. PMID: 27499293
Nota For research use only.
Isotype Control Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)
Imágenes
  • Anti-Human TM4SF20 Recombinant Antibody (SAA1694)

    SDS-PAGE

    SDS-PAGE for Anti-Human TM4SF20 Antibody (SAA1694)

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human TM4SF20 Recombinant Antibody (SAA1694)

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