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Anti-Human TM4SF20 Recombinant Antibody (SAA1694) (HS891013)

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Anti-Human TM4SF20 Recombinant Antibody (SAA1694)
Anti-Human TM4SF20 Recombinant Antibody (SAA1694)
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Aperçu
Numéro de catalogueHS891013
Description
Anti-Human TM4SF20 Recombinant Antibody (SAA1694) (HS891013) is a mouse monoclonal antibody detecting TM4SF20 in ELISA. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
Reactivité des espècesHuman
ApplicationsELISA
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a, kappa
ID de cloneSAA1694
Cible Transmembrane 4 L6 family member 20, TM4SF20
Niveau d'endotoxines < 10 EU/mg as determined by LAL method.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès Q53R12
RRID Anti-Human TM4SF20 Antibody (SAA1694) (abinScience Cat# HS891013, RRID:AB_3727455)
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Transmembrane 4 L6 family member 20 (TM4SF20) is a ~25 kDa protein. Polytopic transmembrane protein that inhibits regulated intramembrane proteolysis (RIP) of CREB3L1, inhibiting its activation and the induction of collagen synthesis. In response to ceramide, which alters TM4SF20 membrane topology, stimulates RIP activation of CREB3L1. Ceramide reverses the direction through which transmembrane helices are translocated into the endoplasmic reticulum membrane during translation of TM4SF20, this mechanism is called 'regulated alternative translocation' (RAT) and regulates the function of the transmembrane protein.

1. Chen, Q. et al. (2014) PloS one 9, e108528. PMID: 25310401
2. Chen, Q. et al. (2016) Molecular cell 63, 567-578. PMID: 27499293
Note For research use only.
Isotype Control Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)
Images
  • Anti-Human TM4SF20 Recombinant Antibody (SAA1694)

    SDS-PAGE

    SDS-PAGE for Anti-Human TM4SF20 Antibody (SAA1694)

Reférences
Fiche technique
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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