Anti-Human TMEFF1 Recombinant Antibody (30C10) (HP664107)

Name: Anti-Human TMEFF1 Recombinant Antibody (30C10)
Brand: abinScience
SKU: HP664107
Price: 191 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HP664107
Reactivité des espèces	Human
Applications	ELISA, FCM
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG2a, kappa
ID de clone	30C10
Cible	C9orf2, H7365, TMEFF1, TR-1, Transmembrane protein with EGF-like and one follistatin-like domain, Tomoregulin-1
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q8IYR6
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	Tomoregulin-1 (TMEFF1) is a ~40 kDa protein. Neuron-specific restriction factor that prevents herpes simplex virus 1 (HHV-1) infection in the brain by blocking viral entry. Also able to restrict herpes simplex virus 2 (HHV-2) infection, although to a lesser extent. Acts by preventing the association between the viral glycoprotein D (gD) and its cell surface receptor NECTIN1, thereby inhibiting fusion of the virus and the cell membrane. Also able to prevent the association between the viral glycoprotein B (gB) and MYH9/NMMHC-IIA and MYH10/NMMHC-IIB receptors. May be a tumor suppressor in brain cancers. 1. Dai, Y. et al. (2024) Nature 632, 383-389. PMID: 39048823 2. Chan, YH. et al. (2024) Nature 632, 390-400. PMID: 39048830 3. Gery, S. et al. (2003) Oncogene 22, 2723-7. PMID: 12743596
Note	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Human TMEFF1 Antibody (30C10)

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Anti-Human TMEFF1 Recombinant Antibody (30C10).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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