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| カタログ番号 | HA136013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human, Mouse | ||||
| アプリケーション | ELISA, FCM, SPR | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1912 | ||||
| ターゲット | TMEM106B, Transmembrane protein 106B | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q9NUM4, Q80X71 | ||||
| RRID | Anti-Human TMEM106B Antibody (SAA1912) (abinScience Cat# HA136013, RRID:AB_3727676) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Transmembrane protein 106B (TMEM106B) is a ~31 kDa protein. In neurons, involved in the transport of late endosomes/lysosomes. May be involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking. May act as a molecular brake for retrograde transport of late endosomes/lysosomes, possibly via its interaction with MAP6. In motoneurons, may mediate the axonal transport of lysosomes and axonal sorting at the initial segment. It remains unclear whether TMEM106B affects the transport of moving lysosomes in the anterograde or retrograde direction in neurites and whether it is important in the sorting of lysosomes in axons or in dendrites. 1. Stagi, M. et al. (2014) Molecular and cellular neurosciences 61, 226-40. PMID: 25066864 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human TMEM106B Antibody (SAA1912)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
