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Anti-Human TMEM70 Polyclonal Antibody (HP775014)

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Aperçu
Numéro de catalogueHP775014
Description
Anti-Human TMEM70 Polyclonal Antibody (HP775014) is a rabbit polyclonal antibody detecting TMEM70 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human TMEM70 (Thr163-Lys260).
Cible TMEM70, Transmembrane protein 70, mitochondrial
Purification Purified by antigen affinity column.
Numéro d'accès Q9BUB7
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Transmembrane protein 70, mitochondrial (TMEM70) is a ~28 kDa protein. Scaffold protein that participates in the c-ring assembly of mitochondrial ATP synthase (F(1)F(0) ATP synthase or complex V) by facilitating the membrane insertion and oligomer formation of the subunit c/ATP5MC1 through its interaction. Therefore, participates in the early stage of mitochondrial ATP synthase biogenesis and also protects subunit c/ATP5MC1 against intramitochondrial proteolysis. In addition, binds the mitochondrial proton-transporting ATP synthase complexes I and may play a role in the stability of its membrane-bound subassemblies.

1. Kovalčíkova, J. et al. (2019) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 33, 14103-14117. PMID: 31652072
2. Sánchez-Caballero, L. et al. (2020) Biochimica et biophysica acta. Bioenergetics 1861, 148202. PMID: 32275929
3. Bahri, H. et al. (2021) Biochimica et biophysica acta. Molecular cell research 1868, 118942. PMID: 33359711
4. Carroll, J. et al. (2021) Proceedings of the National Academy of Sciences of the United States of America 118. PMID: 33753518
5. Cízková, A. et al. (2008) Nature genetics 40, 1288-90. PMID: 18953340
6. Hejzlarová, K. et al. (2011) Biochimica et biophysica acta 1807, 144-9. PMID: 20937241
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human TMEM70 Polyclonal Antibody

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