Anti-Human TMPRSS2 Recombinant Nanobody (SAA2324) (HT176013)

Name: Anti-Human TMPRSS2 Recombinant Nanobody (SAA2324)
Brand: abinScience
SKU: HT176013
Price: 191 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HT176013

Descripción

Anti-Human TMPRSS2 Nanobody (SAA2324) [SAA2324] (HT176013) is a human monoclonal antibody detecting TMPRSS2 in ELISA, Inhibition. Suitable for Human.

Reactividad de especies

Alpaca

Aplicaciones

ELISA, Inhibition

Especie huésped

Human

Clonalidad

Monoclonal

Isotipo

VHH-His

ID de clon

SAA2324

Objetivo

Transmembrane protease serine 2, EC:3.4.21.122, Serine protease 10, Transmembrane protease serine 2 non-catalytic chain, Transmembrane protease serine 2 catalytic chain, TMPRSS2, PRSS10

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Purified by Nickel column

Número de acceso

O15393

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Transmembrane protease serine 2 (TMPRSS2) is a ~53 kDa protein. Plasma membrane-anchored serine protease that cleaves at arginine residues. Participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia.