Anti-Human TMPRSS2 Recombinant Nanobody (SAA2324) (HT176013)

Name: Anti-Human TMPRSS2 Recombinant Nanobody (SAA2324)
Brand: abinScience
SKU: HT176013
Price: 191 USD
Availability: InStock

データシート製品共有情報コピー

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50ug
100ug
1mg

数量:

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HT176013

説明

Anti-Human TMPRSS2 Nanobody (SAA2324) [SAA2324] (HT176013) is a human monoclonal antibody detecting TMPRSS2 in ELISA, Inhibition. Suitable for Human.

種反応性

Alpaca

アプリケーション

ELISA, Inhibition

宿主種

Human

クローン性

Monoclonal

アイソタイプ

VHH-His

クローンID

SAA2324

ターゲット

Transmembrane protease serine 2, EC:3.4.21.122, Serine protease 10, Transmembrane protease serine 2 non-catalytic chain, Transmembrane protease serine 2 catalytic chain, TMPRSS2, PRSS10

エンドトキシンレベル

Please contact with the lab for this information.

純度

>95% as determined by SDS-PAGE.

精製

Purified by Nickel column

アクセッション番号

O15393

形態

Liquid

保存バッファー

0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

製品使用情報

アプリケーション	希釈
ELISA	1:2000-1:20000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Transmembrane protease serine 2 (TMPRSS2) is a ~53 kDa protein. Plasma membrane-anchored serine protease that cleaves at arginine residues. Participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia.