中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HX932014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human TNFAIP6 Polyclonal Antibody (HX932014) is a rabbit polyclonal antibody detecting TNFAIP6/TSG-6 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
|
||||||||
| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human TNFAIP6 (His26-Asp248). | ||||||||
| ターゲット | TNF alpha-induced protein 6, TNF-stimulated gene 6 protein, Tumor necrosis factor alpha-induced protein 6, Hyaluronate-binding protein, TSG6, Tumor necrosis factor-inducible gene 6 protein, TNFAIP6, TSG-6 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P98066 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Tumor necrosis factor-inducible gene 6 protein (TNFAIP6/TSG-6) is a ~31 kDa protein. Major regulator of extracellular matrix organization during tissue remodeling. Catalyzes the transfer of a heavy chain (HC) from inter-alpha-inhibitor (I-alpha-I) complex to hyaluronan. Cleaves the ester bond between the C-terminus of the HC and GalNAc residue of the chondroitin sulfate chain in I-alpha-I complex followed by transesterification of the HC to hyaluronan. In the process, potentiates the antiprotease function of I-alpha-I complex through release of free bikunin. Acts as a catalyst in the formation of hyaluronan-HC oligomers and hyaluronan-rich matrix surrounding the cumulus cell-oocyte complex, a necessary step for oocyte fertilization. 1. Mahoney, DJ. et al. (2005) The Journal of biological chemistry 280, 27044-55. PMID: 15917224 2. Kuznetsova, SA. et al. (2008) Matrix biology : journal of the International Society for Matrix Biology 27, 201-10. PMID: 18042364 3. Lawrance, W. et al. (2016) The Journal of biological chemistry 291, 8014-30. PMID: 26823460 4. Forteza, R. et al. (2007) American journal of respiratory cell and molecular biology 36, 20-31. PMID: 16873769 5. Sanggaard, KW. et al. (2010) The Journal of biological chemistry 285, 21988-93. PMID: 20463016 6. Briggs, DC. et al. (2015) The Journal of biological chemistry 290, 28708-23. PMID: 26468290 7. Lesley, J. et al. (2004) The Journal of biological chemistry 279, 25745-54. PMID: 15060082 8. Dyer, DP. et al. (2016) The Journal of biological chemistry 291, 12627-12640. PMID: 27044744 10. Tsukahara, S. et al. (2006) The Biochemical journal 398, 595-603. PMID: 16771708 | ||||||||
| 注意事項 | For research use only. |
お問い合わせ
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
