

| Número de catálogo | HW690014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human TOB1 Polyclonal Antibody (HW690014) is a rabbit polyclonal antibody detecting Protein Tob1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human TOB1 (Met1-Asp116). | ||||||||
| Objetivo | TOB, Protein Tob1, Transducer of erbB-2 1, TOB1, TROB1 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P50616 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Protein Tob1 is a ~38 kDa protein. Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Mediates CPEB3-accelerated mRNA deadenylation by binding to CPEB3 and recruiting CNOT7 which leads to target mRNA deadenylation and decay. 1. Doidge, R. et al. (2012) PloS one 7, e51331. PMID: 23236473 2. Matsuda, S. et al. (1996) Oncogene 12, 705-13. PMID: 8632892 3. Hosoda, N. et al. (2011) The EMBO journal 30, 1311-23. PMID: 21336257 | ||||||||
| Nota | For research use only. |
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