Anti-Human p53 (R175H mutant) Recombinant Antibody (F2) (HY039107)

Name: Anti-Human p53 (R175H mutant) Recombinant Antibody (F2)
Brand: abinScience
SKU: HY039107
Price: 196 USD
Availability: InStock

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Vista general

Número de catálogo	HY039107
Reactividad de especies	Human
Aplicaciones	ELISA, FCM
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a, kappa
ID de clon	F2
Objetivo	Antigen NY-CO-13, Cellular tumor antigen p53, P53, Tumor suppressor p53, TP53, Phosphoprotein p53
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P04637
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.09% Sodium azide. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Cellular tumor antigen p53 (TP53) is a ~43 kDa protein. Multifunctional transcription factor that induces cell cycle arrest, DNA repair or apoptosis upon binding to its target DNA sequence. Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Negatively regulates cell division by controlling expression of a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. 1. Guo, A. et al. (2000) Nature cell biology 2, 730-6. PMID: 11025664 2. Bergamaschi, D. et al. (2003) Nature genetics 33, 162-7. PMID: 12524540 3. Louria-Hayon, I. et al. (2003) The Journal of biological chemistry 278, 33134-41. PMID: 12810724 4. An, W. et al. (2004) Cell 117, 735-48. PMID: 15186775 5. Ghosh, A. et al. (2004) Molecular and cellular biology 24, 7987-97. PMID: 15340061 6. Zhao, Y. et al. (2007) The Journal of biological chemistry 282, 11969-81. PMID: 17317671 7. Taira, N. et al. (2007) Molecular cell 25, 725-38. PMID: 17349958 8. Allton, K. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 11612-6. PMID: 19556538 9. Huarte, M. et al. (2010) Cell 142, 409-19. PMID: 20673990 10. Wu, L. et al. (2011) The Journal of biological chemistry 286, 2236-44. PMID: 20959462
Nota	For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human TP53/p53 (R175H mutant) Antibody (F2)

Referencias

Datasheet

Anti-Human p53 (R175H mutant) Recombinant Antibody (F2).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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C₁ × V₁ = C₂ × V₂

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C₁ (Stock Conc.)

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Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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