Anti-Human TRBC2 Recombinant Antibody (SAA1764) (HP477013)

Name: Anti-Human TRBC2 Recombinant Antibody (SAA1764)
Brand: abinScience
SKU: HP477013
Price: 110 USD
Availability: InStock

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Спецификация:

20ug
50ug
100ug
1mg

Количество:

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SDS

Обзор

Каталожный номер

HP477013

Описание

Anti-Human TRBC2 Recombinant Antibody (SAA1764) (HP477013) is a mouse monoclonal antibody detecting TRBC2 in ELISA. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.

Реактивность видов

Human

Применения

ELISA

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a, kappa

ID клона

SAA1764

Цель

TRBC2, TCRBC2, T cell receptor beta constant 2

Уровень эндотоксинов

< 10 EU/mg as determined by LAL method.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

A0A5B9

RRID

Anti-Human TRBC2 Antibody (SAA1764) (abinScience Cat# HP477013, RRID:AB_3727525)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

T cell receptor beta constant 2 (TRBC2) is a ~19 kDa protein. Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens. Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn, ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.

1. Lefranc, MP. (2014) Frontiers in immunology 5, 22. PMID: 24600447

2. Rossjohn, J. et al. (2015) Annual review of immunology 33, 169-200. PMID: 25493333

3. Brownlie, RJ. et al. (2013) Nature reviews. Immunology 13, 257-69. PMID: 23524462

4. Nikolich-Zugich, J. et al. (2004) Nature reviews. Immunology 4, 123-32. PMID: 15040585

Примечание

For research use only.

Isotype Control

Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human TRBC2 Antibody (SAA1764).

Ссылки

Даташит

Anti-Human TRBC2 Recombinant Antibody (SAA1764).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human TRBC2 Recombinant Antibody (SAA1764) (HP477013)

Обзор

Изображения

Ссылки

Даташит

SDS