Anti-Human TRIM11 Polyclonal Antibody (HP506014)

Name: Anti-Human TRIM11 Polyclonal Antibody
Brand: abinScience
SKU: HP506014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HP506014

Reactividad de especies

Human, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human TRIM11 (Asn297-Arg456).

Objetivo

Tripartite motif-containing protein 11, RING-type E3 ubiquitin transferase TRIM11, TRIM11, RING finger protein 92, RNF92, E3 ubiquitin-protein ligase TRIM11, Protein BIA1

Purificación

Purified by antigen affinity column.

Número de acceso

Q96F44

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

E3 ubiquitin-protein ligase TRIM11 is a ~52 kDa protein. E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation pathway. Mediates MED15 ubiquitination leading to proteasomal degradation.

1. Ishikawa, H. et al. (2006) FEBS letters 580, 4784-92. PMID: 16904669

2. Uchil, PD. et al. (2008) PLoS pathogens 4, e16. PMID: 18248090

3. Liu, T. et al. (2016) Cell reports 16, 1988-2002. PMID: 27498865

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human TRIM11 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo