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Anti-Human TRIM22 Polyclonal Antibody (HC134014)

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Anti-Human TRIM22 Polyclonal Antibody
Anti-Human TRIM22 Polyclonal Antibody
Precio(USD): --
Especificación:
  • 50ug
  • 100ug
Número:
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Vista general
Número de catálogoHC134014
Descripción
Anti-Human TRIM22 Polyclonal Antibody (HC134014) is a rabbit polyclonal antibody detecting TRIM22. Suitable for Human.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human TRIM22 (Ser317-Ser498).
Objetivo 50 kDa-stimulated trans-acting factor, E3 ubiquitin-protein ligase TRIM22, EC:2.3.2.27, RING finger protein 94, RING-type E3 ubiquitin transferase TRIM22, RNF94, STAF50, Staf-50, TRIM22, Tripartite motif-containing protein 22
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q8IYM9
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

E3 ubiquitin-protein ligase TRIM22 is a ~56 kDa protein. Interferon-induced E3 ubiquitin ligase that plays important roles in innate and adaptive immunity. Restricts the replication of many viruses including HIV-1, encephalomyocarditis virus (EMCV), hepatitis B virus (HBV), hepatitis C virus (HCV) or Zika virus (ZIKV). Mechanistically, negatively regulates HCV replication by promoting ubiquitination and subsequent degradation of viral NS5A. Also acts by promoting the degradation of Zika virus NS1 and NS3 proteins through proteasomal degradation. Acts as a suppressor of basal HIV-1 LTR-driven transcription by preventing Sp1 binding to the HIV-1 promoter.

1. Yang, C. et al. (2016) Cellular & molecular immunology 13, 94-102. PMID: 25683609
2. Inoue, A. et al. (2022) Biochimica et biophysica acta. Molecular cell research 1869, 119318. PMID: 35777501
3. Zu, S. et al. (2022) Cell & bioscience 12, 139. PMID: 36042495
4. Turrini, F. et al. (2015) Retrovirology 12, 104. PMID: 26683615
5. Fei, X. et al. (2022) Molecular therapy oncolytics 26, 413-428. PMID: 36159777
Nota For research use only
Imágenes
  • Anti-Human TRIM22 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-TRIM22 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Hela cell lysate
    Lane 2: K562 cell lysate
    Lane 3: HL-60 cell lysate
    Lane 4: Mouse thymus lysate
    Lane 5: Mouse lung lysate

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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