Anti-Human TRIM33 Polyclonal Antibody (HP145014)

Name: Anti-Human TRIM33 Polyclonal Antibody
Brand: abinScience
SKU: HP145014
Price: 168 USD
Availability: InStock

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100ug

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Aperçu

Numéro de catalogue

HP145014

Description

Anti-Human TRIM33 Polyclonal Antibody (HP145014) is a rabbit polyclonal antibody detecting TRIM33 in ELISA, IHC, WB. Suitable for Human, Mouse, and Xenopus laevis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human TRIM33 (Asp882-Ala1087).

Cible

TRIM33, RFG7, KIAA1113, RET-fused gene 7 protein, Tripartite motif-containing protein 33, RING-type E3 ubiquitin transferase TRIM33, E3 ubiquitin-protein ligase TRIM33, Protein Rfg7, TIF1-gamma, Ectodermin homolog, TIF1G, Transcription intermediary factor 1-gamma

Purification

Purified by antigen affinity column.

Numéro d'accès

Q9UPN9

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

E3 ubiquitin-protein ligase TRIM33 is a ~122 kDa protein. Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade.

1. He, W. et al. (2006) Cell 125, 929-41. PMID: 16751102

Note

For research use only.

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