Anti-Human TRIM40 Polyclonal Antibody (HB364014)

Name: Anti-Human TRIM40 Polyclonal Antibody
Brand: abinScience
SKU: HB364014
Price: 96 USD
Availability: InStock

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Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HB364014

Descripción

Anti-Human TRIM40 Polyclonal Antibody (HB364014) is a rabbit polyclonal antibody detecting E3 ubiquitin ligase TRIM40; 2.3.2.27; Probable E3 NEDD8-protein ligase; RING finger protein 35; TRIM40; RNF35 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant human TRIM40 (Met1-Leu258).

Objetivo

E3 ubiquitin ligase TRIM40; 2.3.2.27; Probable E3 NEDD8-protein ligase; RING finger protein 35; TRIM40; RNF35

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

Q6P9F5

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

E3 ubiquitin ligase TRIM40 is a ~29 kDa protein. E3 ubiquitin-protein ligase that plays a role in the limitation of the innate immune response. Mediates inhibition of the RLR signaling pathway by ubiquitinating RIGI and IFIH1 receptors, leading to their proteasomal degradation. Also promotes the neddylation of IKBKG/NEMO, stabilizing NFKBIA, and thereby inhibiting of NF-kappa-B nuclear translocation and activation.

1. Noguchi, K. et al. (2011) Carcinogenesis 32, 995-1004. PMID: 21474709

2. Zhao, C. et al. (2017) Cell reports 21, 1613-1623. PMID: 29117565

Nota

For research use only

Imágenes

Western blot

Western blot analysis was performed using anti-TRIM40 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse liver lysate
Lane 2: Rat liver lysate

Referencias

Datasheet

Anti-Human TRIM40 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo