Anti-Human TRIO Recombinant Antibody (SAA1532) (HF906013)

Name: Anti-Human TRIO Recombinant Antibody (SAA1532)
Brand: abinScience
SKU: HF906013
Price: 196 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HF906013

Reactividad de especies

Human

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

SAA1532

Objetivo

TRIO, Triple functional domain protein, PTPRF-interacting protein

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

O75962

RRID

Anti-Human TRIO Antibody (SAA1532) (abinScience Cat# HF906013, RRID:AB_3727293)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Triple functional domain protein (TRIO) is a ~346 kDa protein. Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases. Involved in coordinating actin remodeling, which is necessary for cell migration and growth. Plays a key role in the regulation of neurite outgrowth and lamellipodia formation. In developing hippocampal neurons, limits dendrite formation, without affecting the establishment of axon polarity. Once dendrites are formed, involved in the control of synaptic function by regulating the endocytosis of AMPA-selective glutamate receptors (AMPARs) at CA1 excitatory synapses.

1. Deinhardt, K. et al. (2011) Science signaling 4, ra82. PMID: 22155786

2. Pengelly, RJ. et al. (2016) Journal of medical genetics 53, 735-742. PMID: 27418539

3. Debant, A. et al. (1996) Proceedings of the National Academy of Sciences of the United States of America 93, 5466-71. PMID: 8643598

4. Seipel, K. et al. (1999) Journal of cell science 112 ( Pt 12), 1825-34. PMID: 10341202

5. Barbosa, S. et al. (2020) American journal of human genetics 106, 338-355. PMID: 32109419

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human TRIO Antibody (SAA1532)

Referencias

Datasheet

Anti-Human TRIO Recombinant Antibody (SAA1532).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo