Anti-Human TRIO Recombinant Antibody (SAA1532) (HF906013)

Name: Anti-Human TRIO Recombinant Antibody (SAA1532)
Brand: abinScience
SKU: HF906013
Price: 196 USD
Availability: InStock

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50ug
100ug
1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HF906013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1532

Cible

TRIO, Triple functional domain protein, PTPRF-interacting protein

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

O75962

RRID

Anti-Human TRIO Antibody (SAA1532) (abinScience Cat# HF906013, RRID:AB_3727293)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Triple functional domain protein (TRIO) is a ~346 kDa protein. Guanine nucleotide exchange factor (GEF) for RHOA and RAC1 GTPases. Involved in coordinating actin remodeling, which is necessary for cell migration and growth. Plays a key role in the regulation of neurite outgrowth and lamellipodia formation. In developing hippocampal neurons, limits dendrite formation, without affecting the establishment of axon polarity. Once dendrites are formed, involved in the control of synaptic function by regulating the endocytosis of AMPA-selective glutamate receptors (AMPARs) at CA1 excitatory synapses.

1. Deinhardt, K. et al. (2011) Science signaling 4, ra82. PMID: 22155786

2. Pengelly, RJ. et al. (2016) Journal of medical genetics 53, 735-742. PMID: 27418539

3. Debant, A. et al. (1996) Proceedings of the National Academy of Sciences of the United States of America 93, 5466-71. PMID: 8643598

4. Seipel, K. et al. (1999) Journal of cell science 112 ( Pt 12), 1825-34. PMID: 10341202

5. Barbosa, S. et al. (2020) American journal of human genetics 106, 338-355. PMID: 32109419

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human TRIO Antibody (SAA1532)

Reférences

Fiche technique

Anti-Human TRIO Recombinant Antibody (SAA1532).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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